Lanthanum Carbonate is a medication used as the main active ingredient in medicines to treat with end-stage kidney disease. This component shows a phosphate-binding property. It dissociates gastric acid to release lanthanum ions that bind dietary phosphate.
It inhibits the absorption of phosphate by forming lanthanum-phosphate that decreases concentrations of serum phosphate and calcium phosphate. It treats high phosphate levels, mainly found in people with chronic kidney disease.
Class of Drugs – Phosphate binding agent
Molecular Formula – C3La2O9
Molecular Weight – 457.84 g/mol
Working: This mentioned medicine is an ideal phosphate binder that prevents the absorption of dietary phosphate by producing insoluble lanthanum phosphate. It has been reported that Lanthanum Carbonate binds phosphate at pH 3–5 while maintaining binding activity at pH 1-7.
Uses: Given medication is indicated for the treatment of high blood phosphate levels in people who are on dialysis due to kidney disease. In the process of dialysis, some phosphate removes from the blood, but it is difficult to remove enough to keep the phosphate levels balanced.
Reducing blood phosphate levels can help keep the bones strong, prevent unsafe buildup of minerals in the body, and may decrease the risk of heart disease and strokes that can result from high phosphate levels. It is a natural mineral that binds to phosphate in the foods you eat. The phosphate then passes out of the body in the stool.
Popular Brands and Dosages: Mentioned phosphate-binding active component is used in a popular brand medicine as given below:
- Fosrenol: 500 mg
Tell the doctor about the ongoing treatment with this medicine before having an X-ray of the stomach/abdomen and before surgery.