Active Ingredient: The active ingredient in this medication is Acarbose, which is a pseudotetrasaccharide and inhibitor of alpha-glucosidase and pancreatic alpha-amylase with antihyperglycemic activity. This component binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. It also prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. This drug inhibits pancreatic alpha-amylase which hydrolyzes complex starches to oligosaccharides in the small intestines.
Indications: Acarbose composed Precose is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. It slows the breakdown and absorption of carbohydrates from foods that you eat. This effect helps lessen your blood sugar rise after a meal.
Action Mechanism: The cells lining the small intestine then release alpha-glucosidase enzymes that further digest the oligosaccharides into smaller sugars, like glucose, that can be absorbed. Precose is a man-made oligosaccharide designed to slow down the actions of alpha-amylase and alpha-glucosidase enzymes, thereby slowing the appearance of sugar in the blood after a meal.
Dosages: This effective medicine is available for oral consumption and in dosage as mentioned below:
- 25 mg: It shall be taken exactly as directed by the doctor, usually 3 times daily with the first bite of a meal
- 50 mg: It is to be consumed 3 times a day as prescribed by the doctor
- 100 mg: It is advisable to consume with the first bite of the meal as directed by the doctor
Note: You should not take this medicine if you have inflammatory bowel disease, an ulcer or blockage in your intestines, or cirrhosis of the liver.