Active Ingredient: The mentioned medication contains the main active ingredient, Alendronate Sodium. This active ingredient is the sodium salt of alendronate, a second-generation bisphosphonate and synthetic analog of pyrophosphate. It shows bone anti-resorption activity. This is an enzyme involved in terpenoid biosynthesis. Due to inhibition of this enzyme, it prevents the biosynthesis of isoprenoid lipids that are donor substrates of farnesylation and geranylgeranylation. This results in inhibited and bone resorption and turnover is reduced.
Indications: This is a nonhormonal medication used for the treatment of postmenopausal osteoporosis in women. It helps to build healthy bone, restoring some of the bone loss as a result of osteoporosis. This medication is approved for the prevention and treatment of osteoporosis in postmenopausal women. It increases bone mass and reduces the incidence of fractures, including those of the hip and spine.
Fosamax is also indicated for treatment to increase bone mass in men with osteoporosis. It can be used in the treatment of glucocorticoid-induced osteoporosis and Paget’s disease of bone in men and women. It is useful in people with Paget’s disease of bone who have alkaline phosphatase at least two times the upper limit of normal, or those who are symptomatic, or those at risk for future complications from their disease.
Action Mechanism: The Fosamax pill work as the active ingredient Alendronate sulfate works. It is used to prevent and treat certain types of bone loss in adults. It works by slowing bone loss, which helps to maintain strong bones and reduce the risk of broken bones or fractures.
Dosages: This bisphosphonate medicine is used to treat osteoporosis in adults. Dosages are as follows:
- 10 mg: It is to be administered once a day, after getting up for the day and before taking the first food as prescribed by the doctor
- 70 mg: Recommended to take once a day with a glass of plain water, as mentioned in the prescription by the doctor
Note: Avoid consuming calcium or iron supplements, vitamins, antacids, coffee, tea, soda, mineral water, calcium-enriched juices before or after taking this medicine.