Active Ingredient: This medicine contains active ingredient Methotrexate Sodium. This is an antimetabolite with antineoplastic and immunomodulating properties. This active component acts by binding to and inhibiting the enzyme dihydrofolate reductase. It leads to the inhibition of purine nucleotide and thymidylate synthesis. It also exhibits potent immunosuppressant properties that play the role of dihydrofolate reductase inhibitors.
Indications: Methotrexate composed of medicine is indicated for the treatment of certain types of cancer or to control severe psoriasis or rheumatoid arthritis. Trexall may also be indicated to control juvenile rheumatoid arthritis. It belongs to a class of drugs known as antimetabolites that work by slowing or stopping the growth of cancer cells and suppressing the immune system.
Action Mechanism: This medicine is an antimetabolite that shows its action mechanism as same as its active component. Trexall acts by slowing the growth of certain types of cells, rapidly growing cells, for instance, skin cells, bone marrow cells, and cancer cells. The working of this medicine to treat rheumatoid arthritis, but it’s believed that it decreases the activity of the immune system.
Dosages: This medicine is made available in dosages as mentioned below:
- 2.5 mg: This medicine can be consumed with or without food at any time of the day exactly as mentioned in the prescription by the doctor
- 10 mg: It is to be consumed with or without food at any time of the day as directed by the doctor
Note: This medicine shall not be used in pregnant or breastfeeding women. It may cause a serious health problem.