Generic Trexall


Manufacturer: Azurity Pharmaceuticals

Trexall is a medicinal drug is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. It is composed of active component Methotrexate Sodium that belongs to a group of drugs known as antimetabolites. This medicine is manufactured by one of the well-known pharmaceutical companies, Azurity Pharmaceuticals. It is made available in a conventional tablet as dosages 2.5 mg and 10 mg.

SKU: Azurity Trexall Categories: ,

Available Options

Generic Trexall - 2.5mg

Pack SizePrice/unitPriceQtyAdd to cart
90 pills$0.29$26.10
120 pills$0.28$33.76
180 pills$0.27$48.55
240 pills$0.26$61.94
300 pills$0.24$73.08

Generic Trexall - 10mg

Pack SizePrice/unitPriceQtyAdd to cart
30 pills$0.98$29.40
60 pills$0.95$57.04
90 pills$0.91$82.03
120 pills$0.89$107.02
180 pills$0.87$157.00
240 pills$0.83$199.92


Active Ingredient

This medicine contains active ingredient Methotrexate Sodium. This is an antimetabolite with antineoplastic and immunomodulating properties. This active component acts by binding to and inhibiting the enzyme dihydrofolate reductase. It leads to the inhibition of purine nucleotide and thymidylate synthesis. It also exhibits potent immunosuppressant properties that play the role of dihydrofolate reductase inhibitors.


Methotrexate composed of medicine is indicated for the treatment of certain types of cancer or to control severe psoriasis or rheumatoid arthritis. Trexall may also be indicated to control juvenile rheumatoid arthritis. It belongs to a class of drugs known as antimetabolites that work by slowing or stopping the growth of cancer cells and suppressing the immune system.

Action Mechanism

This medicine is an antimetabolite that shows its action mechanism as same as its active component. Trexall acts by slowing the growth of certain types of cells, rapidly growing cells, for instance, skin cells, bone marrow cells, and cancer cells. The working of this medicine to treat rheumatoid arthritis, but it’s believed that it decreases the activity of the immune system.


This medicine is made available in dosages as mentioned below:

2.5 mg: This medicine can be consumed with or without food at any time of the day exactly as mentioned in the prescription by the doctor

10 mg: It is to be consumed with or without food at any time of the day as directed by the doctor

Note  This medicine shall not be used in pregnant or breastfeeding women. It may cause a serious health problem.


What is Trexall?

Trexall is a medication primarily used to treat cancer, autoimmune diseases, and severe skin conditions. It is available in tablet and injectable forms and belongs to a class of drugs called antimetabolites.

What is Trexall used for?

Cancer Treatment: It is used to treat leukemia, lymphoma, breast cancer, lung cancer, and other types of cancer by inhibiting the growth of cancer cells.

Autoimmune Diseases: Trexall is prescribed for conditions like rheumatoid arthritis, psoriasis, and severe dermatomyositis to suppress the immune system’s activity, reducing inflammation and symptoms.

Severe Skin Conditions: For severe cases of psoriasis that haven’t responded to other treatments, Trexall may be recommended to control symptoms and improve skin health.

What is the generic name of Trexall?

The generic name for Trexall is methotrexate. Methotrexate is also available under different brand names, such as Rheumatrex and Otrexup. It is chemically equivalent to Trexall and serves the same therapeutic purposes.

How does Trexall work?

Trexall works by inhibiting the growth of rapidly dividing cells, including cancer cells and cells involved in autoimmune diseases like rheumatoid arthritis and psoriasis.

What are the common side effects of Trexall?

Common side effects of Trexall may include nausea, vomiting, loss of appetite, fatigue, dizziness, headache, and mouth sores. These side effects are usually temporary and may improve over time.

How long does it take for Trexall to start working?

The onset of action of Trexall varies depending on the condition being treated. Some patients may experience symptom relief within a few weeks, while for others, it may take several months.

Can I drink alcohol while taking Trexall?

It is generally recommended to avoid alcohol while taking Trexall, as it can increase the risk of liver damage and other adverse effects.

Can Trexall interact with other medications?

Yes, Trexall can interact with certain medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and some blood pressure medications. It’s important to inform your healthcare provider about all the medications you are taking before starting Trexall.

What should I do if I miss a dose of Trexall?

If you miss a dose of Trexall, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to catch up. If you are unsure about what to do, consult your healthcare provider or pharmacist for guidance.

Additional information


2.5mg, 10mg


90 pills, 120 pills, 180 pills, 240 pills, 300 pills


$0.29, $0.28, $0.27, $0.26, $0.24


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