Generic Arava


Manufacturer: Mylan Pharmaceutical

Active IngredientLeflunomide
TreatsPsoriatic arthritis · Rheumatoid arthritis drug
Drug ClassPyrimidine Synthesis Inhibitors

Arava is an effective medication that affects the immune system and reduces swelling and inflammation on in the body. It is used to treat the symptoms of rheumatoid arthritis. It has the active ingredient Leflunomide, which is an anti-inflammatory agent. Mylan Pharma, one of the trusted pharmaceutical companies manufactures this medicine. It is made available in dosages like 10 mg and 20 mg.

SKU: Sanofi Arava Categories: ,

Available Options

Generic Arava - 10mg

Pack SizePrice/unitPriceQtyAdd to cart
60 pills$0.46$27.60
90 pills$0.45$40.16
120 pills$0.43$51.34
180 pills$0.42$75.35
240 pills$0.41$98.26
300 pills$0.39$117.30

Generic Arava - 20mg

Pack SizePrice/unitPriceQtyAdd to cart
60 pills$0.61$36.60
90 pills$0.59$53.25
120 pills$0.57$68.08
180 pills$0.56$99.92
240 pills$0.54$130.30
300 pills$0.52$155.55


Active Ingredient

The active component in the medicine is Leflunomide, which is a derivative of isoxazole used for its immunosuppressive and anti-inflammatory properties. It is converted to an active metabolite, which blocks dihydroorotate dehydrogenase, a key enzyme of de novo pyrimidine synthesis, to prevent the expansion of activated T lymphocytes. It inhibits various protein tyrosine kinases, such as protein kinase C to inhibit cell proliferation.


This medication is used to treat rheumatoid arthritis, a condition in which the body’s defense system fails to recognize the body as itself and attacks the healthy tissues around the joints. This medicine helps to reduce joint damage/pain/swelling and helps you to move better. Arava works by weakening your immune system and decreasing swelling.

Action Mechanism

Leflunomide-composed medicine Arava reduces inflammation in the joints that are responsible for both the symptoms of rheumatoid arthritis and the destruction of joints. It reduces symptoms as well as the progressive deformities of the joints caused by arthritis. It reduces inflammation by suppressing the activity of immune cells responsible for the inflammation. It suppresses immune cells by inhibiting dihydroorotate dehydrogenase, an enzyme that is necessary for the production of DNA and RNA. Without DNA and RNA the immune cells cannot multiply or function.

Side Effects

Common Side Effects

  •  Hypertension
  •  Upper Respiratory Infection
  •  Bronchitis
  •  Dyspepsia
  •  Urinary Tract Infection
  •  Alopecia
  •  Back Pain
  •  Dizziness
  •  Skin Rash
  •  Weight Loss
  •  Headache Disorder
  •  Nausea
  •  Vomiting
  •  Diarrhea
  •  Abdominal Pain With Cramps
  •  Hepatitis
  •  Anemia
  •  Symptoms Of Anxiety
  •  Conjunctivitis
  •  Pharyngitis
  •  Rhinitis
  •  Sinusitis
  •  Xerostomia
  •  Aphthous Stomatitis
  •  Gastritis
  •  Gastroenteritis
  •  Constipation
  •  Pruritus Of Skin
  •  Acne Vulgaris
  •  Tenosynovitis
  •  Synovitis
  •  Fever
  •  General Weakness
  •  Malaise
  •  Paresthesia
  •  Anorexia
  •  Tachycardia
  •  Palpitations
  •  Dyspnea
  •  Chest Pain
  •  Flatulence
  •  Bacterial Sepsis
  •  Severe Infection
  •  Pancytopenia
  •  Thrombocytopenic Disorder
  •  Agranulocytosis
  •  Leukopenia
  •  Neutropenic Disorder
  •  Peripheral Neuropathy
  •  Vasculitis
  •  Interstitial Pneumonitis
  •  Pulmonary Fibrosis
  •  Interstitial Lung Disease
  •  Eosinophilia
  •  Erythema Multiforme
  •  Toxic Epidermal Necrolysis
  •  Stevens-Johnson Syndrome
  •  Dry Skin
  •  Arthralgia
  •  Cramps In Legs
  •  Flu-Like Symptoms
  •  Epistaxis
  •  Cough
  •  Abnormal Hepatic Function Tests
  •  Angioedema
  •  Pustular Psoriasis
  •  Reactivated Tuberculosis
  •  Hepatic Failure
  •  Dress Syndrome
  •  Colitis
  •  Pancreatitis
  •  Pulmonary Hypertension
  •  Hyperbilirubinemia

Serious Side Effects, including:

  •  Cough
  •  Numbness/tingling of hands/feet
  •  Hair loss
  •  Chest pain
  •  Fast/pounding heartbeat
  •  Increased thirst/urination
  •  Muscle cramp/pain
  •  Mental/mood changes
  •  Vision changes
  •  Easy bruising/bleeding
  •  Unusual growths/lumps
  •  Unexplained weight loss
  •  Unusual tiredness

Serious Allergic Reactions to this drug, including:

  •  Rash
  •  Itching/swelling
  •  Severe dizziness
  •  Trouble breathing


Before taking this medication, tell your doctor if you’ve had:

  •  Immune system disorder (e.g., HIV infection)
  •  Current/recent infection (e.g., tuberculosis)
  •  Cancer
  •  Bone marrow/blood disorder
  •  Kidney disease
  •  Liver disease (e.g., hepatitis B or C)
  •  Alcohol abuse
  •  Heart disease (e.g., congestive heart failure)
  •  High blood pressure
  •  Lung disease

Products Interaction with this drug:

  •  Warfarin
  •  Rifamycins (e.g., rifampin)
  •  Drugs affecting the liver (e.g., methotrexate)
  •  Cholestyramine
  •  Other drugs that weaken the immune system (e.g., tacrolimus, cyclosporine)


Necessary warning

  •  Warning: Don’t use if you are pregnant, suspect that you are pregnant, or while breastfeeding. Consult your doctor or pharmacist.


  • While using this medication avoid getting pregnant or don’t use it when pregnant/nursing
  • Try not to skip doses
  • Inform the doctor your complete medical history
  • Call MD if new abdominal pain/yellowing eyes/skin
  • If you get a rash, call your doctor immediately


This medication is available for oral consumption and in dosage as mentioned below:

  • 10 mg: It is to be taken with or without food, usually once a day or as directed by the doctor
  • 20 mg: Take this medication once a day before or after a meal as advised by the doctor.

Alternatives Of  Generic Arava


Use birth control to prevent pregnancy while you are taking this medication.


What is Arava?

Arava (leflunomide) affects the immune system and reduces swelling and inflammation in the body. It is used to treat the symptoms of rheumatoid arthritis.

How does Arava work?

The medicine works by suppressing the blood cells that cause inflammation.

How to take Arava medicine?

Arava is consumed only once a day. They are 10 or 20mg each and the usual dose is 20 mg per day. Follow the doctor’s directions. Do not take more or less medicine than prescribed. This medicine can be taken with food.

What about other medications affects Arava consumption?

Arava is often added to current medicines for better control of the disease. Do not stop consuming other medications unless directed by a doctor.

What things are to be taken care of while consuming Arava?

The effects of alcohol could be made worse while taking Arava pills. It is recommended that you minimize alcohol consumption while taking Arava.

Additional information


10mg, 20mg


60 pills, 90 pills, 120 pills, 180 pills, 240 pills, 300 pills


$0.46, $0.45, $0.43, $0.42, $0.41, $0.39


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