Azathioprine medicine is a Purine Antimetabolite and a Nucleic Acid Synthesis Inhibitor. It is a prodrug of mercaptopurine used as an immunosuppressive agent in organ transplantation to accept the foreign organ. In autoimmune diseases, it is used as a corticosteroid-sparing agent.
Class of Drugs – Immunosuppressants
Molecular Formula – C9H7N7O2S
Molecular Weight – 277.27 g/mol
Working: The active component Azathioprine acts by reducing the activity of the body’s immune system. For the treatment of rheumatoid arthritis, this keeps the immune system from attacking and damaging the joints. In the kidney transplant, this medicine keeps the immune system from attacking the newly transplanted kidney.
Uses: Immunosuppressant medicine is approved for the prevention of organ rejection in people who have received a kidney transplant. It can be taken with other medicines so that the new kidney to function normally. It is also used to treat rheumatoid arthritis.
Azathioprine weakens the immune system to help the body accept the new kidney as if it were it’s own or to prevent further damage to the joints in RA.
Popular Brands and Dosages: The mentioned active ingredient is used in popular medicine as mentioned below:
- Imuran: 50 mg
- Prograf: 50 mg
- Rapamune: 50 mg
- Advagraf: 50 mg
This medicine can increase the risk to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others like chickenpox, measles, flu.