Description
Active Ingredient
This given medication composed of a combination of active ingredients, Desogestrel-Ethinyl Estradiol. Ethinyl Estradiol is a semisynthetic estrogen that binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay the progression of prostatic cancer. Desogestrel is a synthetic progestogen structurally related to levonorgestrel, with progesterone hormone receptor agonistic activity, used as a contraceptive and hormone replacement agent. Upon administration, desogestrel binds intracellular progesterone receptors in progesterone responsive tissue and the resultant complex interacts with DNA causing either gene transcription or gene repression.
Indications
This combination hormone medication, Apri is used to prevent pregnancy. It contains 2 hormones: a progestin and an estrogen. It works mainly by preventing the release of an egg (ovulation) during your menstrual cycle. It also makes vaginal fluid thicker to help prevent sperm from reaching an egg (fertilization) and changes the lining of the uterus to prevent attachment of a fertilized egg. If a fertilized egg does not attach to the uterus, it passes out of the body. Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts, and also treat acne. It does not protect you or your partner against sexually transmitted diseases.
Action Mechanism
Desogestrel – ethinyl estradiol composed Apri is an estrogen and progestin combination pill used for the prevention of pregnancy. It works by preventing ovulation and causing changes in the mucus of the cervix that make it difficult for sperm to penetrate and for an egg to implant. It may also be taken to regulate the menstrual cycle.
Dosages
This medicine is available for oral consumption and in dosage as mentioned below:
- 0.15 mg: It is advisable to take as directed by the doctor, usually once a day.
You should not take birth control pills if you have:
- Uncontrolled high blood pressure
- Heart disease
- Hereditary blood disorder
- Circulation problems
- Cancer of the breast, uterus/cervix, or vagina
- Liver disease or liver cancer;
- Severe migraine headaches
- A history of jaundice caused by pregnancy or birth control pills
- If you take any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir (Technivie).
Alternatives Of Apri
Note
If a woman has high blood sugar, talk with the doctor. This medicine may raise blood sugar.
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