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Progesterone is a medicinal drug, which is the therapeutic form of the naturally occurring hormone progesterone. This hormone binds to the progesterone receptor that leads to dissociation of heat shock proteins, receptor phosphorylation, and transcription activation via direct or indirect interaction with transcription factors. This active component exerts inhibitory effects on estrogens by reducing the number of estrogen receptors and maximizing its metabolism to inactive metabolites. This medicine causes secretory changes in the endometrium, reduces uterine contractility during pregnancy, and maintains pregnancy.

Class of Drugs – Hormone

Molecular Formula – C21H30O2

Molecular Weight – 314.5 g/mol

Working: This mentioned medication works by stimulating the further development of blood vessels in the endometrium. Progesterone also stimulates glands in the endometrium to secrete nutrients that nourish the fertilized egg. It prepares the tissue lining of the uterus so that the fertilized egg can be implanted.

Uses: The given medicine is used to treat in women with the absence of menstrual periods i.e. amenorrhea. It can be used as Hormone replacement therapy. Progesterone protects against the side effects of estrogen. Failure to become pregnant within a year of aiming to conceive. It is also used as a part of infertility treatment in women. It can be applied intravaginally and injected it into the muscle may have similar effectiveness for increasing pregnancy rates.

Popular Brands and Dosages: This vital hormonal medicine is used in a popular brand medicine as mentioned below:

  • Prometrium: 200 mg

This medicine may induce many side effects such as stomach upset, changes in appetite, weight gain, fluid retention, swelling, fatigue, acne, drowsiness or insomnia, allergic skin rashes, hives, fever, headache, depression, breast discomfort or enlargement, premenstrual syndrome, contact the doctor immediately.