Hydralazine Hydrochloride is a medicinal drug that shows antihypertensive effects. This drug is used as active component that exerts its vasodilatory effects through modification of the contractile state of arterial vascular smooth muscle. It works by altering intracellular calcium release, and interfering with smooth muscle cell calcium influx. It induces inhibition of phosphorylation of myosin protein or chelation of trace metals necessary for the smooth muscle contraction so as to increase in heart rate, stroke volume and cardiac output. This active component is an arteriolar vasodilator.

Class of Drugs – Vasodilator

Molecular Formula – C₈H₈N₄

Molecular Weight – 160.18 g/mol

Working: The action mechanism of this active component is not known. It is believed that the drug Hydralazine Hydrochloride acts on the blood vessels directly and relaxes them. Due to relaxation of these blood vessels it results in lowering of blood pressure.

Uses: Given medicine can be used with or without other medications for the treatment of high blood pressure. Hydralazine Hydrochloride induces the lowering of the high blood pressure that helps to prevent strokes, heart attacks, and kidney problems. Tis ingredient is vasodilator that works by relaxing blood vessels so blood can flow through the body more easily. Tis smoothen blood flow may help to control the elevated blood pressure.

Popular Brands and Dosages: It is an arteriolar vasodilator used in a popular brand medicine as the main active agent to treat high blood pressure.  It is as given below:

• Apresoline: 25 mg

This medicine may take up to several weeks to show its effectiveness. It is advisable to take this medicine as long as prescribed by the doctor.