Fludrocortisone Acetate is a medication that shows anti-inflammatory and antiallergic activities. It is a glucocorticoid-receptor agonist that binds to cytoplasmic receptors and translocate to the nucleus, which initiates the transcription of glucocorticoid-responsive genes. It inhibits PLA2 activity to prevent the release of arachidonic acid, a precursor of eicosanoids. It also stimulates sodium reabsorption and water retention. It is composed as a conventional tablet form.

Class of Drugs – Corticosteroids

Molecular Formula – C₂₃H₃₁FO₆

Molecular Weight – 422.5 g/mol

Working: This mentioned medication is a steroid drug that belongs to a class of drugs called corticosteroids. In case the body unable to produce enough of a certain steroid hormone, this medicine will help to replace the shortage. This may help the body to perform necessary functions, such as retaining enough salt to function well.

Uses: This medicine is a man-made form of a natural substance made by the body. Fludrocortisone Acetate is used along with other medications to treat low glucocorticoid levels caused by disease of the adrenal gland. It is used in conditions like Addison’s disease, adrenocortical insufficiency, and salt-losing adrenogenital syndrome. Glucocorticoids are needed for the body to function well. It plays a vital role to balance the salt and water in the body and keeping blood pressure normal. They are also necessary to break down carbohydrates in the diet.

Popular Brands and Dosages: Given active component, Fludrocortisone Acetate is a corticosteroid drug used in popular brand medicines as follows:

• Florinef: 0.1 mg
• Medrol: 0.1 mg
• Cortef: 0.1 mg
• Decadron: 0.1 mg