Active Ingredient: The main active ingredient in the medication is Fludrocortisone Acetate. It is the acetate salt of a fluorinated corticosteroid that shows anti-inflammatory and antiallergic activities. It works as a glucocorticoid-receptor agonist that binds to cytoplasmic receptors, translocate the nucleus, and initiates the transcription of glucocorticoid-responsive genes. Due to the inhibition of PLA2 activity, it prevents the release of arachidonic acid, a precursor of eicosanoids. As a mineralocorticoid-receptor agonist, the medication stimulates sodium reabsorption and water retention, potassium and hydrogen secretion in the kidney.
Indications: This medication contains Fludrocortisone, which is a man-made form of a natural substance produced by the body. Florinef is approved for the treatment of low glucocorticoid levels caused by disease of the adrenal gland such as Addison’s disease, adrenocortical insufficiency, salt-losing adrenogenital syndrome. Glucocorticoids are needed in different ways for the body to function well. They are vital components for salt and water balance and to keep blood pressure normal. They are also needed to break down carbohydrates in the diet.
Action Mechanism: This particular drug is a steroid drug that belongs to a class of drugs called corticosteroids. If the body is unable to produce enough steroid hormones, this medication will help to replace the shortage. Florinef may help the body to perform necessary functions, for instance retaining enough salt to function well.
Dosages: This medication is made available in a dosage as follows:
- 0.1 mg: It should be taken by orally with or without food once a day or as directed by the doctor, do not go against it
Note: Do not use this medication in case of a medical condition like a fungal infection in the blood such as candidiasis or valley fever.
What is Florinef?
Florinef is a medication that is used to decrease potassium in the blood. Potassium needs to stay at certain level in the blood so that muscle, especially heart muscle, works properly.
What is Florinef used for?
Fludrocortisone is a corticosteroid. The body shall naturally produce similar corticosteroids that shall help in maintaining the balance of minerals and water for good health. Fludrocortisone makes the kidneys retain sodium, and eliminate potassium through the urine.
What is the dosage pattern with Florinef?
Florinef dosage comes in a .01-mg tablet. Patients take this medication by mouth. Take Florinef exactly as directed. This medication can be taken with or without food.
How to store Florinef?
Store this fludrocortisone medicine at a normal room temperature, away from the reach of moisture and sunlight.
Are there any precautions to be taken while consuming Florinef?
When taking fludrocortisone, limit salt intake; this will help minimize water retention.