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Sirolimus

[ Generic Medicines for Men & Women Treatment ]

Wyeth Rapamune

Sirolimus is an active component that has immunosuppressant properties. This component acts by binding to the immunophilin FK Binding Protein-12 to generate an immunosuppressive complex. This binds to and inhibits the activation of the mammalian Target of Rapamycin, a key regulatory kinase. This process leads to the inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine stimulation and inhibition of antibody production.

Class of Drugs – Immunosuppressant

Molecular Formula – C51H79NO13

Molecular Weight - 914.2 g/mol

Working: This mentioned medication is an immunosuppressant drug. Sirolimus composed medicines work by preventing the white blood cells from getting rid of the transplanted organ.

Uses: This drug is indicated to prevent rejection of a kidney transplant. Sirolimus is an immunosuppressant drug that weakens the defense system i.e. immune system of the body to help the body accept the new organ as if it were it's own.

It may also be used to treat a certain lung disease like lymphangioleiomyomatosis.

Popular Brands and Dosages: Given active component is used in a popular brand medicine as mentioned below:

  • Rapamune: 1 mg

Do not eat grapefruit or drink grapefruit juice while consuming this medication. Grapefruit can increase the risk of side effects.