Selegiline Hydrochloride is an effective medication that shows the antiparkinsonian effect. It is a selective monoamine oxidase inhibitor that has the greatest affinity for type B MAO. It found mainly in the brain. This active factor is converted by MAO B to an active moiety to bind irreversibly at the active site of the enzyme’s cofactor FAD molecule. It prevents the oxidative deamination of catecholamines and serotonin by MAO B, and results in an increase in these neurotransmitters’ activities leads to improved motor function.
Class of Drugs – MAO inhibitor
Molecular Formula – C13H18ClN
Molecular Weight – 223.74 g/mol
Working: This mentioned active component belongs to a group of drugs known as an enzyme blocker i.e. MAO inhibitor. Selegiline Hydrochloride acts by slowing the breakdown of certain natural substances in the brain i.e. neurotransmitters like dopamine, norepinephrine, and serotonin.
Uses: Given the MAO inhibitor drug is indicated for the treatment of movement disorders induced by Parkinson’s disease. It does not cure Parkinson’s disease. Selegiline Hydrochloride may improve shakiness, muscle stiffness, or loss of normal movement. This medicine wears off, and sudden switching between normal movement and stiffness can occur. It improves the range of motion and ability to walk, dress, and exercise.
Popular Brands and Dosages: This active component is used in a popular brand medicine as mentioned below:
- Eldepryl: 5 mg
This medicine can cause dizziness or drowsiness. Do not perform any task that requires alertness or concentration. Do not consume alcohol or alcohol-containing substances; it may cause more dizziness.