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Mefloquine Hydrochloride is piperidinyl quinidine that has antimalarial activity. Although the exact mechanism of this medication is largely unknown, this agent acts as a blood schizonticide and probably exerts its actions by interacting with the phospholipid bilayer to interfere with the stability of the cell membrane and causing cell lysis. It is active against Plasmodium falciparum and Plasmodium vivax.

Class of Drugs – An antimalarial agent

Molecular Formula – C17H17ClF6N2O

Molecular Weight – 414.8 g/mol

Working: This medication is an antimalarial agent that works as a blood schizonticide. It is active against the erythrocytic stages of Plasmodium species. This drug has no effect against the exoerythrocytic stages of the parasite. Mefloquine Hydrochloride is effective against malaria parasites resistant to chloroquine.

Uses: Given medication is indicated for the treatment of mild to moderate acute malaria caused by mefloquine-susceptible strains of P. falciparum both chloroquine-susceptible and resistant strains or by Plasmodium vivax.

Popular Brands and Dosages: This drug Mefloquine Hydrochloride is the anti-malarial medicine is available in a popular brand medicine as given below:

  • Lariam: 250 mg

This medicine is not recommended in pregnant or breastfeeding women unless prescribed by the doctor.