Indomethacin medication is an anti-inflammatory drug with chemopreventive properties. It works as a nonsteroidal anti-inflammatory drug that inhibits the enzyme cyclooxygenase so as to prevent the cyclooxygenase DNA. It inhibits the expression of multidrug-resistant protein type 1 leads to increased efficacies of some antineoplastic agents in treating multi-drug resistant tumors. In addition, this active component activates phosphatases that restrict the migration of cancer cells and obstruct their surviving. It is available as an extended release tablet.
Class of Drugs – A nonsteroidal anti-inflammatory drug
Molecular Formula – C19H16ClNO4
Molecular Weight – 357.8 g/mol
Working: This anti-inflammatory drug works by decreasing the formation of prostaglandins, which are chemicals that the body produces. Indomethacin causes fever and pain that are related to inflammation. This component blocks the enzymes that produce prostaglandins so as to decrease the levels of prostaglandins. It leads to the reduction of fever, pain and inflammation.
Uses: This given active ingredient is a nonsteroidal anti-inflammatory drug. Indomethacin is indicated for the treatment of pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. This medication is also used to relieve pain from various other conditions. It restricts the body’s production of certain natural substances that cause inflammation that helps to decrease swelling and pain.
Popular Brands and Dosages: Tis particular nonsteroidal anti-inflammatory drug is used as the active component in popular brand medicines as given below:
- Indocin: 25 mg, 50 mg, and 75 mg
- Indocin SR: 25 mg, 50 mg, and 75 mg
Do not lie down for at least 10 minutes after administrating this drug. If stomach upset occurs while consuming this medication, consume it with food, milk, or an antacid.