Sildenafil Citrate is an oral phosphodiesterase type 5 (PDE5) inhibitor, which is a medication prescribed for treating erectile dysfunction (ED) or impotence issues in men. Various factors can further influence how long the pill shall stay in the system. These are all important for well considering while further assessing the overall safety. And it shall impact impotence treatment which shall have on a man’s health.
Sildenafil Citrate Working
The medication shall treat the symptoms of impotence. But it is not a cure for the condition of impotence. Impotence issue in men is the persistent inability in achieving and sustaining an erection that is firm enough for having satisfactory sexual lovemaking sessions. For sildenafil to work, sexual arousal is much needed. In an erection, which is known as a chemical messenger it is known as nitric oxide¹ (NO) which is well released. NO shall all relax the trabecula (which shall be well specialized for the muscle/connective tissue fibers) of a particular part of the penile which is known as the called the corpus cavernosum. Which shall be about maximizing blood flow and penile engorgement-like condition.
An erection is much needed, hence the outcome of an adequate arterial flow shall need oxygen to the cavernosa and sufficient nitric oxide that shall generate nitric oxide. Detumescence, however, occurs when some of the intracavernosal type 5 cyclic GMP phosphodiesterase (PDE5), which is known to be an enzyme, that shall break down the cyclic GMP-like condition. This medication shall inhibit PDE5 so that cGMP shall not be metabolized as quickly. And a stiffer penile erection is sustained longer.
The medication does not directly lead to an erection, which will indirectly slow down the breakdown of biochemicals which shall help sustain a stiffer penile erection for a longer time. This medicine is highly successful. One study in men with impotence found the ED medication to have a success rate of 91%.
How Long Will Sildenafil Take To Deliver Effectiveness?
The medicine is well rapidly absorbed and usually, it shall work within an hour. Thus it is highly recommended for being consumed an hour before any planned sexual lovemaking session. However, the medication can simply start working within just 30 minutes of consumption or take up to two hours to work for some individuals.
Study On Sildenafil
- One study has found that around 71% of participants have all experienced penile erection onset in just 30 minutes of consumption.
- Consumption of Sildenafil on an empty stomach shall make this pill work quicker. Eating a high-fat meal before consumption of this ED pill shall slowly help in the absorption of the pill. So it shall take longer to start working well.
- Also, sexual lovemaking sessions are well needed for the ED pill to work well. Finding some of the ways for enhancing sexual lovemaking sessions before sex. Such as acts of foreplay, might help this ED pill to work more quickly.
How Long Will Sildenafil Stay In The System?
The half-life of an ED pill is four hours and it is well typically considered effective for approx. four hours.
For a man who might be sexually aroused and might have had a lovemaking session four hours after consumption of this pill, evidence has suggested. That he shall be still able to achieve a stiffer penile erection that shall last for around 14 minutes.
Effect Of Sildenafil
The medication can stay in the system for about 20 hours. Take the medication for about four to five half-lives for the medication for being eliminated. How long is the medicine effective as it shall differ from person to person?. Some of the FDA labelings have all stated that the ED pill is well effective for Approx four hours. But the effect at four hours is comparatively less than at two hours.
Even though this ED pill can work for four hours, the penile erections shall all typically not last this long. Generally, men might not experience the effects of the ED pill post two to three hours, and penile erection might not be sustained for a longer time than this.
How Often Can Sildenafil be Consumed?
Sildenafil Citrate medication might not have a regular dosing schedule. It might be consumed an hour before the lovemaking session as needed. This shall all means that ED medication is not needed when the man is not struggling to achieve a stiffer penile erection for a longer time.
It is all usually safe for consumption of a dosage of ED pill daily, and many men might consume it for an extended period.
However, this does apply to everyone, hence men must usually check with the healthcare provider to further ensure a safe dosage. That is well based on their medical history. For some the men, such as those who are taking ritonavir-like medication. It is all safe for consuming the ED medicine less usually once every two days. For example, or one might also look for alternative medications as it is well guided by the physician.