Valganciclovir Hydrochloride is a hydrochloride salt form of valganciclovir, a prodrug form of ganciclovir, a nucleoside analog of 2′-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, and viral replication. A ganciclovir prodrug and antiviral agent that is used to treat Cytomegalovirus Retinitis in patients with AIDS, and for the prevention of Cytomegalovirus Infections in organ transplant recipients who have received an organ from a CMV-positive donor.

Class of Drugs – An antiviral drug

Molecular Formula – C₁₄H₂₃ClN₆O₅

Molecular Weight – 390.82 g/mol

Working: This medicine is an antiviral drug that works by preventing viral cells from multiplying in the body. Valacyclovir Hydrochloride is indicated in adults to prevent infection with cytomegalovirus that may occur after an organ transplant such as heart, kidney, or pancreas.

Uses: This antiviral drug. It is changed in the body to the active form of the drug called ganciclovir. Valacyclovir Hydrochloride prevents disease caused by a virus called cytomegalovirus (CMV) in people who have received organ transplants. This disease can lead to serious infections in the body such as infection in the eye, called CMV retinitis, which can cause blindness.

This medicine slows the growth of the CMV virus. It prevents the spread of infection to other areas of the body. It is also used to treat CMV retinitis in people with advanced HIV disease (AIDS). It controls CMV retinitis and reduces the risk of blindness.

Popular Brands and Dosages: It is used in a popular brand medicine as mentioned below:

• Valcyte: 450 mg

This medication is not a cure for CMV disease. It is important to have a seye check-up regularly by while treating with this medicine.