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Trimethoprim

[ Generic Medicines for Bacterial Infections Treatment ]

Trimethoprim is an active ingredient, which is a derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. It acts as a pyrimidine inhibitor of bacterial dihydrofolate reductase. This drug binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this medication is potentiated by sulfonamides. Sulfamethoxazole with it is a fixed antibiotic combination that is widely used for mild-to-moderate bacterial infections and against opportunistic infections.

Class of Drugs – Antibiotics

Molecular Formula – C14H18N4O3

Molecular Weight - 290.32 g/mol

Working: This active medication is an antibiotic that acts by preventing bacteria from forming a substance called folate. In the absence of folate, the bacteria unable to produce DNA and so are unable to grow and increase in numbers. This process of Trimethoprim clears up the infection. This medication shall not be used for future infections. It cannot prevent infections.

Uses: This mentioned antibiotic is indicated to treat bacterial infections. Trimethoprim works by stopping the growth of bacteria. It is recommended to treat only bacterial infections not viral infections like a common cold, flu.

Popular Brands and Dosages: This antibiotic medication is used in popular brand drugs as given below:

  • Proloprim: 100 mg and 200 mg

This medication is not approved for babies below 2 months old. It should not be used to treat an ear infection in a child younger than 6 months old. It should not be used in pregnant women; it may inhibit the growth of the fetus.