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Trazodone Hydrochloride is used as the main active component in medication. It is a synthetic triazolopyridine derivative with antidepressant and sedative properties. This active ingredient selectively inhibits the re-uptake of serotonin by synaptosomes in the brain so as to increase serotonin levels in the synaptic cleft and potentiating serotonin activity. It is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, unable to stimulate the central nervous system. The sedative effect of trazodone is through alpha-adrenergic and mild histamine H1 blocking actions.

Class of Drugs – Selective serotonin reuptake inhibitors

Molecular Formula – C19H23Cl2N5O

Molecular Weight – 408.3 g/mol

Working: This active medicine is indicated to treat the major depressive disorder. This medication may help to improve mood, appetite, and energy level. It also reduces anxiety and insomnia related to depression. Trazodone restores the balance of a certain natural chemical like serotonin in the brain.

Uses: Mentioned medication is an antidepressant that belongs to a group of drugs known as selective serotonin reuptake inhibitors i.e. SSRIs. Trazodone affects chemicals in the brain that may be unbalanced in people with depression. This drug can also be used to treat the major depressive disorder. It improves the quality of life. This medication works by helping to restore the balance of a certain natural chemical in the brain.

Popular Brands and Dosages: This active component is used in a popular brand medicine as mentioned below:

  • Desyre: 50 mg and 100 mg

This medicine should not be used while consuming an MAO inhibitor in the past 14 days. MAO inhibitors may show some serious side effects.