Generic Desyrel


Manufacturer: Bristol-Myers Squibb Pharmaceutical

Desyrel is composed of the main active ingredient, Trazodone Hydrochloride. This active ingredient belongs to a group of drugs called anti-depressant. It is available in a conventional tablet form in dosages of 50 mg and 100 mg.

SKU: Bristol Myers Squibb Desyrel Categories: ,

Available Options

Generic Desyrel - 50mg

Pack SizePrice/unitPriceQtyAdd to cart
90 pills$0.24$21.60
120 pills$0.23$27.94
180 pills$0.22$40.18
240 pills$0.21$51.26
300 pills$0.20$60.48

Generic Desyrel - 100mg

Pack SizePrice/unitPriceQtyAdd to cart
90 pills$0.26$23.40
120 pills$0.25$30.26
180 pills$0.24$43.52
240 pills$0.23$55.54
300 pills$0.22$65.52


Active Ingredient

Trazodone Hydrochloride is a synthetic triazolopyridine derivative that has antidepressant and sedative properties. This medicine inhibits the reuptake of serotonin by synaptosomes in the brain to increase serotonin levels in the synaptic cleft and potentiate serotonin activity. This active ingredient is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs. It does not stimulate the central nervous system.


This mentioned medication is approved to treat depression. This drug may help to improve mood, appetite, and energy levels as well as reduce anxiety and insomnia related to depression. Desyrel helps to restore the balance of a certain natural chemical in the brain.

Action Mechanism

Trazodone composed medicine is an antidepressant drug that affects the chemical messengers i.e. neurotransmitters within the brain that nerves use to communicate with each other. The major neurotransmitters are acetylcholine, norepinephrine, dopamine, and serotonin. Also experts believe that an imbalance among the different neurotransmitters is the cause of depression. Desyrel improves symptoms of depression by inhibiting the uptake of serotonin by nerves in the brain.


Mentioned medicine is made available in dosages as given below:

  • 50 mg: It should be taken orally once or twice a day after a meal or snack or as directed by the doctor
  • 100 mg: It shall be consumed once or twice a day as prescribed by the doctor


This medication is not approved to be consumed by children younger than 18 years old.


What is Desyrel?

Desyrel is used to treat major depressive disorder.

How does Desyrel work?

Desyrel improves symptoms of depression by inhibiting the uptake of serotonin by nerves in the brain. This shall result in more serotonin to stimulate other nerves.

What are the uses for Desyrel?

Trazodone in Desyrel is approved for the treatment of major depression. However, it is most commonly used for treating insomnia. It is also used off-label for treating: Cocaine withdrawal, Alcohol withdrawal, and Prevention of migraine.

What is the dosage for Desyrel?

For the treatment of depression, the dose for adults is 150-600 mg per day of regular tablets. However, the initial starting dose usually is 150 mg per day, which is increased by 50 mg/day every 3-7 days. The tablets are given in one or more daily doses, sometimes with the largest dose at night.

Is trazodone safe to take during pregnancy or breastfeeding?

Trazodone should only be used during pregnancy if the physician feels that its benefits outweigh its potential risks. Trazodone is secreted in breast milk. Therefore, caution should be used in prescribing trazodone to women who are breastfeeding.

Additional information


50mg, 100mg


90 pills, 120 pills, 180 pills, 240 pills, 300 pills


$0.24, $0.23, $0.22, $0.21, $0.20


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