Stavudine is used as the main active ingredient, which is a nucleoside reverse transcriptase inhibitor. This ingredient is used in combination with other medicines in the treatment of human immunodeficiency virus infection and the acquired immunodeficiency syndrome (AIDS). An inhibitor of HIV-1 reverse transcriptase, this active component [plays the role of an antimetabolite, an EC RNA-directed DNA polymerase inhibitor and an antiviral agent.

Class of Drugs – A nucleoside reverse transcriptase inhibitor

Molecular Formula – C₁₀H₁₂N₂O₄

Molecular Weight – 224.21 g/mol

Working: In the condition of HIV, the virus replicates within the cells of the body. The new viruses are released from the cells and expanse throughout the body. In this manner, the infection spreads to new uninfected cells. Reverse transcriptase, an enzyme that the virus needs to form this new DNA. This active component is converted within the body to its active form is used by the HIV virus to form new DNA. Stavudine triphosphate interferes with the action of the reverse transcriptase and does not kill existing HIV virus. This medication is not a cure for HIV.

Uses: This particular medicine is indicated with other HIV drugs to help control HIV infection. This active ingredient decreases the amount of HIV in the body so the immune system can work better. Stavudine reduces the chance of getting HIV complications and improves the quality of life.

Popular Brands and Dosages: This nucleoside reverse transcriptase inhibitor used in a popular brand medicine as mentioned below:

• Zerit: 40 mg

To reduce the risk of spreading HIV disease to others, follow (1) Take all HIV medicines exactly as prescribed by the doctor, (2) Always use an effective barrier method during all sexual activity, and (3) Avoid sharing personal items like needles/syringes, toothbrushes, and razors that may have contacted blood or other body fluids.