Mesalamine is an Aminosalicylate drug used as the main active ingredient in medicines. It is Aminosalicylic Acid and a monohydroxybenzoic acid that is salicylic acid substituted by an amino group. It plays the role of a non-steroidal anti-inflammatory drug. This component is an aromatic amine, an amino acid, a member of phenols, a monocarboxylic acid and a monohydroxybenzoic acid. It derives from salicylic acid.

Class of Drugs – Aminosalicylates

Molecular Formula – C7H7NO3

Molecular Weight – 153.14 g/mol

Working: The mechanism of action of this medication is not known. But it is believed by the scientists that it may work by reducing inflammation in the colon. In conditions like Ulcerative colitis and other inflammatory diseases, excessive production of chemicals occurred. The medication blocks the activity of cyclooxygenase and lipoxygenase so as to reduce the production of prostaglandins. Due to reduction prostaglandins, it decreases the inflammation in the colon and the symptoms of ulcerative colitis

Uses: It is indicated for the treatment of certain bowel diseases such as ulcerative colitis. It reduces symptoms of ulcerative colitis like diarrhea, rectal bleeding, and stomach pain. The pill Mesalamine belongs to a class of drugs known as aminosalicylates. It is helpful to decrease the swelling in the colon.

Popular Brands and Dosages: This effective active component is available in popular brands as mentioned below:

  • Asacol: 400 mg and 800 mg
  • Lialda: 400 mg and 800 mg
  • Apriso: 400 mg and 800 mg
  • Pentasa: 400 mg and 800 mg

Mesalamine should be taken as directed by the doctor, usually 4 times daily.

  • Asacol-800-mg
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    Generic Asacol

    Price range: $22.80 through $71.00
    Active IngredientMesalamine
    TreatsUlcerative colitis · Crohn’s disease
    Drug Class5- Aminosalicylic acid (5-ASA) (Aminosalicylic Acids Derivative)
    • Pregnancy – Mesalazine can be hazardous to use at some stage in pregnancy. But, the blessings from use in pregnant women can be perfect no matter the threat. Please consult your doctor.
    • Lactation – Mesalazine is probably hazardous to apply in the course of lactation.
    • Alcohol – Please seek advice from your health practitioner.
    • Liver Warning – Mesalazine has to be used with warning in patients with liver sickness. Please consult your physician.
    • Kidney Warning – Mesalazine should be used with caution in patients with a kidney disorder. Please seek advice from your health practitioner.

    Asacol is a popular brand of medicine sued to treat Ulcerative Colitis. It is composed of the active ingredient Mesalamine. It affects a substance in the body that causes inflammation, tissue damage, and diarrhea. Asacol tablets are used to treat moderately active ulcerative colitis in adults. It is manufactured by the leading pharmaceutical company, Apil Pharmaceuticals. It is offered in a conventional tablet and dosages of 400 mg and 800 mg.

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