Active Ingredient: It is composed of active component Mesalamine. It is an agent derived from sulfasalazine, an antiinflammatory agent. It may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. It helps to reduce bowel inflammation, diarrhea, rectal bleeding and stomach pain.
Indications: Given medication is used to treat a certain bowel disease such as ulcerative colitis. Asacol helps to reduce symptoms of ulcerative colitis such as diarrhea, rectal bleeding, and stomach pain. This medication belongs to a class of drugs known as aminosalicylates that decreases swelling in the colon.
Action Mechanism: The absorbed medication is rapidly acetylated in the gut mucosal wall and by the liver. It is excreted mainly by the kidney as N-acetyl-5-aminosalicylic acid. Mesalamine from orally administered Asacol tablets appears to be more extensively absorbed than the mesalamine released from sulfasalazine.
Dosages: This medication is available for oral consumption and in dosage as mentioned below:
- 400 mg: It is an oral medication shall be taken with or without food as directed by the doctor, usually 3 times a day
- 800 mg: It is to be consumed 3 times a day before or after meal as directed by the doctor
Note: Do not give this medicine to a child without medical advice.
What is Asacol?
Asacol (mesalamine) affects a substance in the body that causes inflammation, tissue damage, and diarrhea. They are used to treat moderately active ulcerative colitis in adults.
How to consume Asacol?
Take Asacol exactly as prescribed by your doctor. Take the tablets with a full glass of water. Take tablets on an empty stomach, at least 1 hour before and 2 hours after a meal.
What is to be avoided while taking Asacol?
Ask doctor before using an antacid and use only the type doctor recommends. Some antacids can make it harder for the body to absorb mesalamine.
What other drugs will affect Asacol?
Inform the doctor about current medicines and any start or stop using, especially: azathioprine; mercaptopurine; or NSAIDs.
Are Asacol safe to take while pregnant or breastfeeding?
There are no adequate human studies of mesalamine during pregnancy. Mesalamine is known to cross the placenta into the fetus, but animal studies revealed no evidence of harm to the fetus. Mesalamine is excreted in breast milk.