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Hydroxyzine is an antihistamine medication that has antiemetic and anxiolytic properties. Its antihistaminic effect is due to its metabolite, cetirizine, a potent H1 receptor antagonist and selective inhibitor of peripheral H1 receptors. This active component competes with histamine for binding at H1-receptor sites on the effector cell surface. It occurs as a result of the suppression of certain subcortical regions of the brain.

Class of Drugs – Antihistamine

Molecular Formula – C21H27ClN2O2

Molecular Weight – 374.9 g/mol

Working: The histamine released by the body during several types of allergic reactions and, to a lesser extent, during viral infections, like the common cold. This component binds to its receptors on cells, it causes the cells to release chemical messengers that result in sneezing, itching, and increased mucus production. It binds to the histamine receptors. This active ingredient Hydroxyzine is a drug called cetirizine that acts as antihistamines and causes more sedation than cetirizine.

Uses: Given medication is cetirizine, which is indicated to treat itching caused by allergies. This drug is an antihistamine and acts by blocking a certain natural substance like histamine that the body produces during an allergic reaction. Hydroxyzine may also be indicated to treat anxiety or to help you feel sleepy/relaxed before and after surgery.

Popular Brands and Dosages: This active ingredient is used in a popular brand medicine as follows:

  • Atarax: 10 mg, 25 mg, and 50 mg

This drug may impair thinking or reactions. Be careful while driving or doing anything that requires alertness.