Dutasteride is a synthetic 4-azasteroid compound intended as the main active component in medicines. It is approved in the treatment enlarged prostate. It binds to isoenzymes 1 and 2 of 5 alpha-reductase forming stable enzyme complexes and inhibiting the conversion of testosterone to 5 alpha-dihydrotestosterone. The reduction in DHT activity may mitigate or prevent enlargement of the prostate gland. The type reductase iso-enzyme is primarily active in the reproductive tissues, while the type 1 isoenzyme is also active in the skin and the liver.
Class of Drugs – 5-Alpha-reductase Inhibitors
Molecular Formula – C27H30F6N2O2
Molecular Weight – 528.5 g/mol
Working: This active ingredient belongs to a class of drugs called 5 alpha-reductase inhibitors. There’s a hormone in your blood called dihydrotestoterone (DHT) that causes the prostate to grow. Dutasteride prevents the formation of DHT in your body, causing an enlarged prostate to shrink.
Uses: This mentioned active medication is used in men to treat the symptoms of an enlarged prostate i.e. benign prostatic hyperplasia. Dutasteride works by reducing the size of the enlarged prostate. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently including during the middle of the night. It may also reduce the need for surgery to treat BPH.
This component is not approved for the prevention of prostate cancer. It may slightly increase the risk of developing a very serious form of prostate cancer. Talk to your doctor about the benefits and risks.
Popular Brands and Dosages: This drug is used in a popular brand medication as mentioned below:
- Avodart: 0.5 mg