[ Generic Medicines for Alzheimer Treatment ]
Tetrabenazine is a vesicular monoamine transporter type 2 inhibitors are agents that induce depletion of neuroactive peptides like dopamine in nerve terminals and are indicated to treat chorea due to neurodegenerative diseases like Huntington chorea or dyskinesias due to neuroleptic medications. It is approved to decrease the uncontrolled movements caused by Huntington's disease.
Class of Drugs – Dopamine Depleter
Molecular Formula – C19H27NO3
Molecular Weight - 317.4 g/mol
Working: This is an active component, which is dopamine deplete medicine. This active component Tetrabenazine works by inhibiting the vesicular monoamine transporter 2. Neurons are connected to each other by synapses and able to communicate via chemical signals called neurotransmitters. VMAT2 is responsible for regulating the neurotransmitters and its released across the synapse.
Uses: Given active medication is indicated to reduce the uncontrollable movements like chorea caused by Huntington's disease. This is not a cure for the disease. Decreasing the chorea will help to take part in more of normal daily activities. Tetrabenazine is thought to act by reducing the amount of certain natural substances in the brain monoamines such as dopamine, serotonin, and norepinephrine, which are involved with nerve and muscle function. This medication belongs to a group of drugs called monoamine depletors.
Popular Brands and Dosages: This monoamine depletory medicine is made available in a popular brand medicine as given below:
- Xenazine: 25 mg
This drug is not recommended in people who have severe or untreated depression, suicidal thoughts, liver disease.