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Rosiglitazone Maleate

[ Generic Medicines for Diabetes Treatment ]

Rosiglitazone Maleate is an orally-active thiazolidinedione that shows anti-diabetic properties and potential antineoplastic activity. This is an active ingredient that activates peroxisome proliferator-activated receptor-gamma, a ligand-activated transcription factor, so as to induce cell differentiation and inhibiting cell growth and angiogenesis. This component also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation.

Class of Drugs – Antidiabetics

Molecular Formula – C22H23N3O7S

Molecular Weight - 473.5 g/mol

Working: This medicine is a diabetes medicine that helps control blood sugar levels. Rosiglitazone Maleate is indicated together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It is not for treating type 1 diabetes. This drug is not recommended for use with insulin.

Uses: Given medication is approved with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling blood sugar prevents kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper treatment of diabetes may also lessen the risk of a heart attack or stroke. Rosiglitazone Maleate belongs to the group of drugs known as glitazones. This lowers blood sugar by helping to restore the body's proper response to insulin.

Popular Brands and Dosages: It is used as the main active component in a popular brand medicine as given below:

  • Avandia: 2 mg, 4 mg, and 8 mg

This medicine shall be taken with proper diet and exercise. Do not eat food item, which contains sugar or glucose. It may increase the extra amount of sugar in the body.