Active Ingredient: The active component of this medicine is Rosiglitazone Maleate, which is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. It induces cell differentiation and inhibiting cell growth and angiogenesis. This component also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation.
Indications: Rosiglitazone composed Avandia is used with a proper diet and exercise program to control high blood sugar in people with type-2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. This medicine belongs to the class of drugs known as glitazones. It lowers blood sugar by helping to restore your body’s proper response to insulin.
Action Mechanism: is an oral antidiabetic medication that acts primarily by increasing insulin sensitivity. Avandia improves glycemic control while reducing circulating insulin levels.
Dosages: This glitazones medicine is available for oral consumption and in dosage as mentioned below:
- 2 mg: It is an oral drug shall be taken with or without food as directed by the doctor, usually once or twice a day
- 4 mg: It is to be consumed with or without food exactly as prescribed by the doctor
Note: Given medicine can cause or worsen congestive heart failure. It shall not be used if you have severe or uncontrolled heart failure.