The active component in the mentioned medication is Glimepiride. It is a long-acting medicine with hypoglycemic activity. This active component is metabolized by CYP2C9 and shows peroxisome proliferator-activated receptor-gamma agonistic activity. It lowers the blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells and increases the sensitivity of peripheral tissues to insulin.
Amaryl also binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface which reduces potassium conductance and causes depolarization of the membrane.
This medication is indicated with a proper diet and exercise to control high blood sugar in people with type 2 diabetes. It can also be used with other diabetes medicines. Controlling high blood sugar prevents kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
Controlling diabetes also lessens the risk of a heart attack or stroke. It belongs to a group of drugs known as sulfonylureas. It lowers blood sugar by causing the release of the body’s natural insulin.
This mentioned medication Amaryl helps the pancreas to release insulin. Insulin is a chemical that the body produces to move sugar from the bloodstream into cells. Once the sugar enters cells, they can use it as fuel for the body. With type 2 diabetes, the body doesn’t produce enough insulin, or it can’t properly use the insulin that it produces, so the sugar stays in the bloodstream. This causes high blood sugar levels.
This particular medication is available in various dosages as mentioned below:
- 1 mg: It is to be consumed orally with breakfast or the first main meal of the day, as advised by the doctor.
Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. This drug can increase the sensitivity to sunlight.