Rifaximin is an antibiotic medication derived from rifamycin SV with antibacterial activity. This active medicine binds to the beta-subunit of bacterial DNA-dependent RNA polymerase. It inhibits the bacterial RNA synthesis and bacterial cell growth. It is unable to absorb; therefore, its antibacterial activity is largely retaining at the gastrointestinal tract. This active component is used as treatment and prevention of travelers’ diarrhea. It can also be used for prevention of hepatic encephalopathy in people with severe liver disease and to treat diarrhea in people with irritable bowel syndrome.

Class of Drugs – Antibiotic

Molecular Formula – C₄₃H₅₁N₃O₁₁

Molecular Weight – 785.9 g/mol

Working: Given antibiotic is active against Escherichia coli bacterial strains that can develop traveler’s diarrhea. It acts by preventing growth of the bacteria by restricting them from producing proteins essential for their replication and survival. Through suppressing growth of the bacteria, this medication decreases symptoms of traveler’s diarrhea. The condition of hepatic encephalopathy is a serious neurologic disorder of severe liver disease that affects the brain. It may cause due to absorption of ammonia and other chemicals made by bacteria in the intestine. Rifaximin prevents and treats hepatic encephalopathy by decreasing the intestinal bacteria that form ammonia.

Uses: This particular medicine is indicated for the treatment of treat diarrhea induced by the common bacteria known as E. coli. This drug should not be used in case of a fever or bloody diarrhea. Rifaximin stops the growth of bacteria. It is recommended for bacterial infections only, not for viral infections like common cold, flu. This medication can be used to treat irritable bowel syndrome with diarrhea. It prevents a brain problem caused by liver disease and may help to think more clearly.

Popular Brands and Dosages: This antibiotic is used in a popular brand medicine as given below:

• Xifaxan: 200 mg and 550 mg

It is advisable to avoid any immunizations/vaccinations while treating with this medication unless the doctor advised for.