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Orlistat is a reversible active-site inhibitor of gastrointestinal lipases. This is an active ingredient used in the medication for weight loss. It forms a covalent bond with the active serine site in gastric and pancreatic lipases so as to inhibit their activity and preventing dietary fat from being hydrolyzed.  It is an inhibitor of pancreatic and gastric lipase and a commonly used weight loss agent that is available both by prescription and over-the-counter.

Class of Drugs – An active-site inhibitor

Molecular Formula – C29H53NO5

Molecular Weight – 495.7 g/mol

Working: This medicine helps to lose weight effectively. This medication works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. Orlistat composed medicine does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.

Uses: This medication is approved by the doctor for weight loss along with exercise. This needs behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Taking Orlistat composed medicine can also help keep you from gaining back weight you have lost. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.

Popular Brands and Dosages: This cancer drug is used in a popular brand medication as mentioned below:

  • Xenical: 120 mg