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Naltrexone Hydrochloride is a noroxymorphone derivative that shows competitive opioid antagonistic activity. It also binds to various opioid receptors in the central nervous system CNS, such as kappa- and gamma-opioid receptors. This active component is longer-acting and more potent compared to naloxone. It is a mu-opioid receptor antagonist that is indicated to treat alcohol dependence. It plays the role of a mu-opioid receptor antagonist, an antidote to opioid poisoning and a central nervous system depressant.

Class of Drugs – Opiate antagonists

Molecular Formula – C20H24ClNO4

Molecular Weight – 377.9 g/mol

Working: This medication actively blocks the feel-good response to alcohol causes. Active component Naltrexone Hydrochloride might help reduce the urge to drink and prevent excessive alcohol consumption. It works effectively to live without a satisfying an urge to drink alcohol.

Uses: It is prescribed to prevent people who have been addicted to certain drugs like opiates from consuming them again. It is consumed as part of a complete treatment program for drug abuse. It can be used as compliance monitoring, counseling, behavioral contract, lifestyle changes. This drug must not be used in people currently treating with opiates, like methadone. It may cause sudden withdrawal symptoms.

This drug is an opiate antagonist. It acts in the brain to prevent opiate effects that decrease the desire to take opiates.

It can be used to treat alcohol abuse. It can help people drink less alcohol and reduce the desire to drink alcohol.

Popular Brands and Dosages: This active component is used in a popular brand drug as given below:

  • Revia: 50 mg

It should not be given to nursing mothers; it may pass through breast milk and harm a nursing infant.