Ziprasidone is an atypical antipsychotic medication that shows an antischizophrenic property. This active component functions as an antagonist at the dopamine D2, serotonin 5-HT2A, and 5-HT1D receptors. It acts as an agonist at the 5-HT1A receptor. This medicine inhibits the synaptic reuptake of serotonin and norepinephrine. It potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. It also shows antagonistic activity against histamine H1 and alpha-1-adrenergic receptors.

Class of Drugs – Atypical antipsychotic

Molecular Formula – C₂₁H₂₁ClN₄OS

Molecular Weight – 412.9 g/mol

Working: The action mechanism of this active ingredient is by blocking receptors on the nerves for several neurotransmitters. These chemicals are that are responsible for the communication of nerves with each other. It is the beneficial effect of this medication due to its blocking of dopamine and serotonin receptors. Ziprasidone acts by inhibiting the reuptake of serotonin and norepinephrine by nerves in the brain such as some anti-depressant drugs. It is related to little or no weight gain, a feature that distinguishes it from other antipsychotic drugs.

Uses: This mentioned medicine is approved for the treatment of certain mental/mood disorders such as schizophrenia or bipolar disorder. Ziprasidone can reduce hallucinations and helps to think more clearly and positively about oneself, feel less agitated, and inspire to take a more active part in everyday life.

This medicine is an atypical antipsychotic drug works by restoring the balance of certain natural substances in the brain.

Popular Brands and Dosages: This active component is used in a popular brand medicine as mentioned below:

• Geodon: 20 mg, 40 mg, 60 mg, and 80 mg

Get medical attention right away if the experienced constant fever that does not go away, mental/mood changes, headache, or dizziness. It is unique among antipsychotic drugs that do not increase cholesterol levels.