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Sitagliptin Phosphate

[ Generic Medicines for Diabetes Treatment ]

Sitagliptin Phosphate is an active component used in medicines to treat beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 that has hypoglycemic activity. It may cause an increased risk in the development of pancreatitis. A pyrazine-derived dipeptidyl-peptidase inhibitor as well as a hypoglycemic agent that maximizes the levels of the incretin hormones glucagon- and glucose-dependent insulinotropic polypeptide. This medication is indicated in the treatment of type 2 diabetes.

Class of Drugs – Dipeptidyl peptidase-4 inhibitors

Molecular Formula – C16H18F6N5O5P

Molecular Weight - 505.31 g/mol

Working: This medication belongs to a group of medicines called dipeptidyl peptidase-4 inhibitors.  Insulin, which is a chemical in the body helps remove sugar from the blood and moves it to cells. It can be used for energy. Hormones in the body known as incretins. It regulates the production and release of insulin. Sitagliptin Phosphate acts by protecting incretin hormones from broken down too quickly. It helps the body utilize insulin better and reduces blood sugar.

Uses: This mentioned medication is approved for the treatment of type 2 diabetes. It should be taken with a proper diet and exercise program. Sitagliptin Phosphate can be taken with other medications to control high blood sugar. Controlling blood sugar prevents kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Control of diabetes may also lessen the risk of a heart attack or stroke.

This drug works by increasing levels of natural substances called incretins that control blood sugar by increasing insulin release, after a meal.

Popular Brands and Dosages: This active component is used in a popular brand medicine as given below:

  • Januvia: 25 mg and 50 mg

Regularly check the blood sugar as directed by the doctor and share the results from time to time.