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Alendronate

[ Generic Medicines for Osteoporosis Treatment ]

Alendronate Sodium is used as the main active ingredient in medicines to treat osteoporosis in adults. This active ingredient is the sodium salt of alendronate, bisphosphonate and a synthetic analog of pyrophosphate with bone anti-resorption activity. It binds to and inhibits the activity of geranyl trans transferase, an enzyme involved in terpenoid biosynthesis. Due to the inhibition of this enzyme, the biosynthesis of isoprenoid lipids is prevented.

Class of Drugs – Bisphosphonates

Molecular Formula – C4H12NNaO7P2

Molecular Weight - 271.08 g/mol

Working: This given medicine acts by slowing bone loss. It maintains strong bones and reduces the risk of broken bones. This component Alendronate Sodium belongs to a class of drugs called bisphosphonates.

Uses: The mentioned medication is indicated to prevent and treat certain types of bone loss i.e. osteoporosis in adults. This causes bones to become thinner and break more easily. The chance of developing osteoporosis increases with increasing age, after menopause.

Popular Brands and Dosages: Bisphosphonate medicine Alendronate Sodium is used in the popular brand medicines as mentioned below:

  • Fosamax: 10 mg and 70 mg
  • Atelvia: 10 mg and 70 mg
  • Actonel: 10 mg and 70 mg
  • Boniva: 10 mg and 70 mg

Do not consume alendronate and call the doctor at once in case experience chest pain, new or worsening heartburn, or pain when swallowing. Avoid taking this pill if difficulty to sit upright or stand for at least 30 minutes after taking the medicine.