Active Ingredient: Sorafenib Tosylate a component targeting growth signaling and angiogenesis. This active medication blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation. It also inhibits the VEGFR-2/PDGFR-beta signaling cascade to block the tumor angiogenesis. It is an organosulfonate salt.
Indications: This mentioned medicine is indicated for the treatment of cancer that interferes with the growth and spread of cancer cells in the body. Nexavar is an effective drug approved to treat liver cancer, thyroid cancer, or kidney cancer.
Action Mechanism: Sorafenib Tosylate composed of medicine may interfere with 2 signaling pathways in cancer cells and tumor blood vessels. It acts by inhibiting tumor cell signals, reducing cancer cell growth and division. Nexavar decreases the formation of new blood vessels that provide oxygen and nutrients needed for cancer cells to keep growing. After slowing down tumor growth and decreasing the blood supply to the tumor, it prevents the growth and spread of cancer. It is also important to normal cells.
Dosages: This cancer-treating medication is available in a dosage as mentioned below:
- 200 mg: It must be consumed on an empty stomach at least 1 hour before or 2 hours after a meal or twice a day as directed by the doctor
Note: It is not recommended in people with squamous cell lung cancer and who are being treated with carboplatin and paclitaxel.