Active Ingredient: The main active component is Allopurinol, which is a structural isomer of hypoxanthine. This component inhibits xanthine oxidase, an enzyme that converts oxypurinol to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, so as to provide protection against uric acid-mediated end-organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies.
Indications: Allopurinol composed medication Zyloprim is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. These people can have increased uric acid levels due to the release of uric acid from dying cancer cells. This medicine works by reducing the amount of uric acid made by the body. Increased uric acid levels can cause gout and kidney problems.
Action Mechanism: This medication is a xanthine oxidase inhibitor and is similar to febuxostat. Uric acid is a by-product of the breakdown of certain proteins in the body by enzymes called xanthine oxidases. Hyperuricemia occurs when the body produces more uric acid than it can eliminate. The uric acid forms crystals in joints and tissues, causing inflammation and pain. Elevated blood uric acid levels also can cause kidney disease and kidney stones. Zyloprim prevents the production of uric acid by blocking the activity of the enzymes that converts purines to uric acid.
Dosages: This gout treating medication is available for oral consumption and in dosage as mentioned below:
- 100 mg: It is to be consumed once a day or as directed by the doctor. Take this medication after a meal to reduce stomach upset
- 300 mg: This medicine shall be taken once a day with food as advised by the doctor
Note: It is recommended to follow a special diet while treating with this medication. Follow all instructions of the doctor.
What is Zyloprim used for?
Zyloprim is an effective medication commonly used to treat gout, a condition where high levels of uric acid in the body result in crystals forming in the joints and skin.
What is the dosage for Zyloprim?
The dose of Zyloprim for treating gout is 200-600 mg daily depending on severity.
What are the side effects of Zyloprim?
Like all medicines, it can potentially cause some side effects. The side effects experienced may vary among individuals and in rare instances, serious skin reactions, reduced blood count and/or liver disorder may occur.
Special use of Zyloprim
Zyloprim is also used for preventing the elevation of blood uric acid in patients undergoing chemotherapy for the treatment of certain cancers and in patients with recurrent calcium kidney stones and elevated uric acid levels.
Which drugs or supplements interact with Zyloprim?
Zyloprim increases blood levels of oral mercaptopurine (Purinethol) and azathioprine (Imuran) by reducing their breakdown in the body.