Active Ingredient: The main active component is Colchicine, which is an alkaloid isolated from Colchicum autumnale with anti-gout and anti-inflammatory activities. The exact mechanism of action by which colchicines exerts its effect has not been completely established. This active ingredient binds to tubulin, so as to interfere with the polymerization of tubulin, interrupting microtubule dynamics, and disrupting mitosis. This leads to an inhibition of the migration of leukocytes and other inflammatory cells, thereby reducing the inflammatory response to deposited urate crystals.
Indications: Given medication is intended to prevent or treat gout attacks. Usually, gout symptoms develop suddenly and involve only one or a few joints. The big toe, knee, or ankle joints are most often affected. Gout is caused by too much uric acid in the blood. When uric acid levels in the blood are too high, the uric acid may form hard crystals in your joints.
Action Mechanism: This medicine belongs to a class of drugs called anti-gout medications. The way Colcrys works is not fully understood. It may prevent some of the body’s immune cells from causing pain and inflammation. It works by decreasing swelling and lessening the buildup of uric acid crystals that cause pain in the affected joint(s). This medication is also used to prevent attacks of pain in the abdomen, chest, or joints caused by a certain inherited disease. It is thought to work by lowering your body’s production of a certain protein that builds up in people with familial Mediterranean fever.
Dosages: This Colcrys medication is available for oral consumption and in dosage as mentioned below:
- 0.5 mg: This anti-gout medication is to be consumed with or without food, exactly as directed by the doctor
Note: This medicine is not a cure for gouty arthritis or Behcets syndrome, and it will not prevent these diseases from progressing.