Active Ingredient: Ranolazine is the main active component of this medicine. It is a piperazine derivative with anti-anginal and potential antineoplastic properties. This medication may involve the alteration of the trans-cellular late sodium current in the ischemic myocyte. By preventing the rise of intracellular sodium levels, this drug may affect the transport activity of sodium-dependent calcium channels. It also prevents calcium overload during myocardial ischemia to prevent cellular injury. Its potential antineoplastic effect may depend on its inhibitory effect on fatty acid oxidation. This sensitizes tumor cells to apoptosis and reduces tumor cell proliferation; fatty acid oxidation provides energy and promotes tumor cell proliferation and survival.
Indications: Ranolazine composed of medicine is indicated for the treatment of chronic angina or chest pain. Ranexa acts by improving blood flow to help the heart work more efficiently. This medicine is not for treating during an acute attack of angina.
Action Mechanism: This mentioned medicine is an anti-anginal drug that works by improving blood flow to help the heart work more efficiently and smoothly. Ranexa is approved for the treatment of chronic angina.
Dosages: This medicine is available for administration in dosages as given below:
- 500 mg: This is an extended-release tablet, usually taken twice a day with or without food at around the same times every day as prescribed by the doctor
- 1000 mg: This medicine is to be taken twice a day before or after a meal as advised by the doctor
Note: This medicine is not recommended in people who have cirrhosis of the liver.
What is Ranexa used for?
Ranexa is used to treat chronic angina (chest pain). It works by improving blood flow to help the heart work more efficiently.
How to consume Ranexa?
Take Ranexa exactly as prescribed by your doctor. Ranexa may be taken with or without food. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Call the doctor if your symptoms do not improve, or if they get worse while using Ranexa.
What is the dosage of Ranexa?
The typical starting dose is 500 mg orally twice daily. If needed, the doctor might increase it to 1000 mg orally twice daily.
What is to be avoided while taking Ranexa?
Ranexa may impair thinking or reaction act. Be careful while driving or performing anything that needs alertness. Grapefruit and grapefruit juice may interact with Ranexa and lead to unwanted side effects. Discuss the use of grapefruit products with the doctor.
What happens in case of overdose with Ranexa?
Overdose can lead to nausea, vomiting, numbness or tingling, dizziness, double vision, confusion, or fainting.