The main active component of this medicine is Cyclophosphamide, which is a synthetic alkylating agent chemically related to nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, this agent is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
It is a synthetic nitrogen mustard alkylating agent, with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to active metabolites including phosphoramide mustard, which binds to and crosslinks DNA and RNA, thereby inhibiting DNA replication and protein synthesis.
Cyclophosphamide composed of the medicine Cytoxan is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cell growth.
This drug also works by decreasing your immune system’s response to various diseases. It is used to treat a certain type of kidney disease in children after other treatments have not worked.
Metabolites interfere with malignant cell growth by cross-linking tumor cell DNA; the drug does not have specificity for any phase of the cell cycle; it also has potent immunosuppressive activity. Cyclophosphamide-composed drug Cytoxan is an alkylating agent of the nitrogen mustard type. An activated form of cyclophosphamide, phosphoramide mustard, alkylates, or binds, to DNA. Its cytotoxic effect is mainly due to the cross-linking of strands of DNA and RNA and to inhibition of protein synthesis.
This Cytoxan medicine is available for oral consumption and in dosage as mentioned below:
- 50 mg: Given the conventional tablet is recommended to consume orally exactly as directed by the doctor
During treatment with given medication, a person must drink more fluids than usual and pass urine frequently to help avoid kidney and bladder side effects.
What is Cytoxan?
Cytoxan is an anti-cancer chemotherapy drug. This medication is classified as an alkylating agent.
What Cytoxan is used for?
Cancers treated with Cytoxan include Hodgkin’s and non-Hodgkin’s lymphoma, Burkitt’s lymphoma, chronic lymphocytic leukemia (CLL), chronic myelocytic leukemia (CML), acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), t-cell lymphoma (mycosis fungoides), multiple myeloma, neuroblastoma, retinoblastoma, breast cancer, ovarian cancer, and conditioning regimens for bone marrow transplantation.
How Cytoxan is given?
Tablets should be given with food or after meals. Tablets should not be cut or crushed. The dosage depends on many factors, including height and weight, general health or other health problems, and the type of cancer or other condition.
How Cytoxan works?
Cytoxan is classified as an alkylating agent. Alkylating agents weaken or destroy breast cancer cells by damaging the cells’ genetic material.