Catapres is a popular brand medication for the treatment of high blood pressure. It is composed with an active ingredient Clonidine Hydrochloride. This medication is manufactured by the top pharmaceutical company, Boehringer Ingelheim. It is made available in a conventional tablet form in a dosage of 0.1 mg.
Manufacturer: Boehringer Ingelheim
Active Ingredient: The main active ingredient of this medicine is Clonidine Hydrochloride, which is the hydrochloride salt form of clonidine, an imidazoline derivate, and centrally-acting alpha-adrenergic agonist as well as antagonist with antihypertensive activity. This component binds to and stimulates central alpha-2 adrenergic receptors, thereby decreasing sympathetic outflow to the heart, kidneys, and peripheral vasculature. The reduction in sympathetic outflow leads to decreased peripheral vascular resistance, decreased blood pressure, and decreased heart rate.
Indications: This given medication is used alone or with other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Clonidine belongs to a class of drugs that act in the brain to lower blood pressure. Catapres relaxes blood vessels so blood can flow more easily.
Action Mechanism: This mentioned medication Catapres acts on a central sympatholytic via stimulation of central alpha receptors; results in reduced sympathetic outflow, causing decreased PVR, HR, BP, and renal vascular resistance; produces presynaptic and postjunctional alpha-2 adrenoreceptor analgesia by preventing pain signal transmission to the brain.
Postsynaptic alpha2-agonist stimulation may regulate subcortical activity in the prefrontal cortex, which may regulate the area of the brain responsible for attention, emotions, and behaviors, and so as to reduce hyperactivity, distractibility, and impulsiveness.
Dosages: This medication is available for oral consumption and in dosage as mentioned below:
- 0.1 mg: It is to be administered orally with or without food as directed by the doctor, usually twice a day in the morning and at bedtime
Note: This medication may impair thinking or reactions. It is advisable to be cautious while driving or doing anything that requires alertness.