Description
Active Ingredient
The main active component of this medicine is Procyclidine Hydrochloride. It is a tertiary alcohol that plays the role of a muscarinic antagonist, an anti-Parkinson drug, and an anti-dyskinesia agent. It is also a member of pyrrolidines. A muscarinic antagonist that crosses the blood-brain barrier and is indicated in the treatment of drug-induced extrapyramidal disorders and parkinsonism.
Indications
Procyclidine composed of medicine is indicated in the treatment of symptoms of Parkinson’s disease or involuntary movements caused by the side effects of certain psychiatric drugs like chlorpromazine/haloperidol. Kemadrin belongs to a class of drugs called anticholinergics that work by blocking a certain natural substance like acetylcholine. It also helps reduce muscle stiffness, sweating, and the production of saliva and improves walking ability in people with Parkinson’s disease.
Anticholinergics stop severe muscle spasms of the back, neck, and eyes that are sometimes induced by psychiatric drugs. It decreases other side effects like muscle stiffness/rigidity.
Action Mechanism
This mentioned medication works by blocking the receptors that acetylcholine acts on. Kemadrin reduces the activity of acetylcholine and restores the balance of acetylcholine and dopamine in the brain. Due to a decrease in dopamine, it can produce side effects that resemble the symptoms of Parkinson’s disease.
Side Effects
- Dryness in mouth
- Nausea
- Blurred vision
- Dizziness
- Lightheadedness
- Dilatation of pupil
- Epigastric pain
Dosages
This effective drug is made available in dosage as given below:
- 5 mg: It is an oral drug that should be taken 3 to 4 times a day after meals and at bedtime or as directed by the doctor
Note
It should not be used in angle-closure glaucoma. This medication does not help treat movement problems induced by tardive dyskinesia and may worsen them.
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