Depakote ER is manufactured by one of the global pharmaceutical company, Abbott Laboratories. It is composed of the main active ingredient Divalproex Sodium. This medication is indicated for the treatment of epilepsy and seizures. Available dosages of this pill are 125 mg, 250 mg, and 500 mg.
Manufacturer: Abbott Laboratories
Active Ingredient: The main active ingredient of this pill is Divalproex Sodium. It is a stable coordination compound comprised of sodium valproate and valproic acid. It shows the properties of anticonvulsant and antiepileptic. The active component dissociates to the valproate ion in the gastrointestinal tract. It also binds to and inhibits gamma-aminobutyric acid transaminase.
The anticonvulsant activity of the ingredient exerted by increasing the brain concentration of GABA. It also inhibits enzymes that catabolize GABA or blocks the reuptake of GABA into glia and nerve endings. This medication may also suppress the repetitive neuronal firing through inhibition of voltage-sensitive sodium channels.
Indications: This given medicine is valproate, which is approved for the treatment of acute manic or mixed episodes related to bipolar disorder, with or without psychotic features. It is useful to treat typical signs of mania such as the pressure of speech, grandiosity, motor hyperactivity, possible hostility, poor judgment, reduced need for sleep, the flight of ideas, and aggressiveness.
Depakote ER may also be used as monotherapy and adjunctive therapy in the treatment of people with complex partial seizures. It can be used as sole and adjunctive therapy in the treatment of simple and complex absence seizures.
Prophylaxis of migraine headaches can be treated with the given medication Depakote ER.
Action Mechanism: The mentioned medicine is approved for the treatment of seizure disorders, mental/mood conditions like the manic phase of bipolar disorder, and to prevent migraine headaches. This effective pill works by restoring the balance of certain natural substances like neurotransmitters in the brain.
Dosages: The antiepileptic medication is available in the form of a conventional tablet. Dosages are available as follows:
- 125 mg: It is to be consumed once a day as directed by the doctor
- 250 mg: Take this medicine with food to avoid stomach upset exactly as prescribed by the doctor
- 500 mg: Recommended dose of this pill is once a day as directed by the doctor
Note: This medicine is not suitable for children below 10 years of age.