Active Ingredient: Desmopressin Acetate is the main active ingredient used in the given medicine. It is a synthetic analog of arginine vasopressin (ADH), is an antidiuretic peptide drug. The endogenous pituitary hormone, ADH has the control of water content in the body. After releasing from the stimulation of increased plasma osmolarity or reduced circulating blood volume, ADH mainly acts on the cells of the distal part of the nephron. The hormone interacts with receptors and differing signal cascade systems.
Indications: This effective medication is approved for controlling the amount of urine the kidneys produce. Usually, the amount of urine produced in the body is controlled by a certain substance in the body called vasopressin. In people who have water diabetes or certain kinds of head injury or brain surgery, the body does not produce enough vasopressin. This active component is a man-made form of vasopressin and is used to replace a low level of vasopressin. It also controls increased thirst and too much urination due to these conditions and prevents dehydration.
DDAVP can be used to control nighttime bedwetting in children. It decreases how often the child urinates and decreases the number of bedwetting episodes.
Action Mechanism: The active component of this medicine, Desmopressin Acetate helps to release of von Willebrand’s antigen from the platelets and the cells that line the blood vessels. This antigen is the protein that carries factor VIII and increases in von Willebrand’s antigen and factor VIII. It helps to stop bleeding. The medicine works quickly, with a peak effect in 60 minutes. It can stop bleeding in people with von Willebrand’s disease or mild hemophilia A.
Dosages: This given effective conventional tablet DDAVP is used to controlling the amount of urine the kidneys produce. It is available in a dosage as follows:
- 0.2 mg: This medicine should be administered with or without food as mentioned in the prescription by the doctor
Note: Above mentioned tablets should be used with caution in people with conditions associated with fluid and electrolyte imbalance, such as cystic fibrosis, heart failure, and renal disorders.