Given medicine is a combination of two active ingredients. Dipyridamole is a synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. It inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate. It inhibits the stimulation of platelet aggregation by agents such as platelet activating factor and collagen.
Aspirin is a non-steroidal antiinflammatory agent that binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation.
Given medication is approved to reduce the risk of stroke in patients who have had “mini-strokes” or a previous stroke due to a blood clot and are at high risk for another stroke. This medicine composed of two components. It works to keep blood flowing to the brain by stopping platelets from clumping together. Aggrenox prevents the platelets from forming blood clots, which can lodge in the brain and cause a certain type of stroke (ischemic stroke).
This medicine a combination of is an aspirin/extended-release dipyridamole combination that acts on multiple mechanisms of the platelet-aggregation process to prevent clumping and clotting.
This medication Aggrenox is available for oral consumption and in dosage as mentioned below:
- 200 mg + 25 mg: It is an oral drug shall be taken with or without food as directed by the doctor, usually twice a day.
Common Side Effects
- Acute Abdominal Pain
- Thrombocytopenic Disorder
- Pruritus Of Skin
- Skin Rash
- Headache Disorder
- Biliary Calculus
- Acute Confusion
- Laryngeal Edema
Serious Side Effects, including
- Easy bleeding/bruising
- Uncontrolled bleeding from gums or nose
- Fast/slow/irregular heartbeat
- Loss of appetite
- Dark urine
- Yellowing eyes/skin
- Unusual tiredness
- Unusual weakness
- Signs of kidney problems
This drug may rarely cause serious bleeding from the stomach or intestines.
- Black stools
- Persistent stomach/abdominal pain
- Symptoms of a heart attack
- Signs of bleeding in the brain or stroke
Symptoms Of A Serious Allergic Reaction, including:
- Severe dizziness
- Trouble breathing
Tell your doctor if you’ve had:
- Kidney disease
- Liver disease
- A certain muscle problem (myasthenia gravis)
- Aspirin-sensitive asthma
- Bleeding problems (such as hemophilia, vitamin K deficiency, low platelets)
- Low blood pressure (hypotension)
- Heart problems (such as angina, heart attack)
- Stomach problems (such as ulcers, heartburn)
- Growths in the nose (nasal polyps)
- Bleeding in the brain
Interactions with this drug include:
- Corticosteroids (such as prednisone)
- Ginkgo biloba
- Swallow whole.
- Do not chew or crush.
- May cause dizziness
- Medication should be taken with plenty of water.
- Do not take aspirin products without doctor approval.
- Patients regularly using NSAIDs and this drug may be at a greater risk for
- Stomach bleeding.
- Do not lie down for at least 10 minutes after taking this drug.
- May make you dizzy.
- Use caution when driving.
- Tell your pharmacist & Dr if you have allergies
- Do not chew or crush
- Swallow capsules whole.
- Take with a full glass of water (8 ounces)
- Call Dr if you have black stools or stomach pain
- Limit alcohol consumption and stop using tobacco.
- Tell Dr/dentist on drug prior to any surgery.
You should not take this medicine if you have asthma and also have polyps in your nose.