Active Ingredient: The main active ingredient in the given medicine is Esomeprazole Magnesium. This active ingredient is the magnesium salt of esomeprazole with gastric proton pump inhibitor activity. It is converted into the active achiral sulphonamide that forms one or more covalent disulphide bonds with the proton pump hydrogen-potassium adenosine triphosphatase so as to inhibit its activity. The parietal cell secretion of H+ ions into the gastric lumen.
Indications: This medication is approved for the treatment certain stomach and esophagus problems like acid reflux, ulcers. This medicine acts by reducing the amount of acid the stomach produces. Nexium relieves symptoms like heartburn, difficulty swallowing, and persistent cough.
It helps to heal acid damage to the stomach and esophagus, prevents ulcers, and prevents cancer of the esophagus. This mentioned active ingredient belongs to a class of drugs known as proton pump inhibitors also treats frequent heartburn.
Action Mechanism: This medicine reduces the amount of acid the stomach produces. It works by blocking the proton pump in the cells of the stomach. When the proton pump is blocked, the stomach produces less acid.
Dosages: This medicine is available in following dosages:
- 20 mg: Take this medicine as directed by the doctor, usually once daily, at least 1 hour before a meal
- 40 mg: It should be administered exactly as prescribed by the doctor, do not go against it
Note: Proton pump inhibitors can increase the risk for bone fractures, especially with longer use, higher doses, and in older adults. Take calcium supplements or consult the doctor.