Florinef is an effective medication used to treat low glucocorticoid levels caused by disease of the adrenal gland. It is composed of Fludrocortisone Acetate as the main active component. This active component is a steroid drug. It is manufactured by a well-known pharmaceutical company, Bristol-Myers Squibb. It is available in the form of a conventional tablet for oral consumption in a dosage of 0.1 mg.
Manufacturer: Bristol-Myers Squibb
Active Ingredient: The main active ingredient in the medication is Fludrocortisone Acetate. It is the acetate salt of a fluorinated corticosteroid that shows anti-inflammatory and antiallergic activities. It works as a glucocorticoid-receptor agonist that binds to cytoplasmic receptors, translocate the nucleus, and initiates the transcription of glucocorticoid-responsive genes. Due to the inhibition of PLA2 activity, it prevents the release of arachidonic acid, a precursor of eicosanoids. As a mineralocorticoid-receptor agonist, the medication stimulates sodium reabsorption and water retention, potassium and hydrogen secretion in the kidney.
Indications: This medication contains Fludrocortisone, which is a man-made form of a natural substance produced by the body. Florinef is approved for the treatment of low glucocorticoid levels caused by disease of the adrenal gland such as Addison's disease, adrenocortical insufficiency, salt-losing adrenogenital syndrome. Glucocorticoids are needed in different ways for the body to function well. They are vital components for salt and water balance and to keep blood pressure normal. They are also needed to break down carbohydrates in the diet.
Action Mechanism: This particular drug is a steroid drug that belongs to a class of drugs called corticosteroids. If the body is unable to produce enough steroid hormones, this medication will help to replace the shortage. Florinef may help the body to perform necessary functions, for instance retaining enough salt to function well.
Dosages: This medication is made available in a dosage as follows:
- 0.1 mg: It should be taken by orally with or without food once a day or as directed by the doctor, do not go against it
Note: Do not use this medication in case of a medical condition like a fungal infection in the blood such as candidiasis or valley fever.