Zocor is composed of active ingredient Simvastatin, belongs to a class of drugs known as HMG CoA reductase inhibitors. This medicine has manufactured by the leading pharmaceutical company, Merck Sharp & Dohme Corp. It is indicated for the treatment of high blood cholesterol in the body. It is available in a conventional tablet form in dosages of 5 mg, 10 mg, and 20 mg.
Manufacturer: Merck Sharp & Dohme Corp.
Active Ingredient: Simvastatin is an active ingredient of the fungus Aspergillus terreus. This drug inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. It lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells.
Indications: Given medication belongs to a class of drugs called HMG CoA reductase inhibitors, or statins. Zocor is intended to lower blood levels of bad cholesterol or low-density lipoprotein, or LDL, to increase levels of good cholesterol i.e. high-density lipoprotein, or HDL. It lowers triglycerides, a type of fat in the blood. It is also indicated to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors. This medicine is used in adults and children above 10 years old.
Action Mechanism: Simvastatin composed medicine is an HMG-CoA reductase inhibitor. Zocor works by slowing the formation of cholesterol in the body to reduce the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.
Dosages: This drug is made available in dosages as mentioned below:
- 5 mg: It should be taken once a day in the evening exactly as mentioned below
- 10 mg: This drug shall be consumed once a day wit or without food, as directed by the doctor
- 20 mg: It is to be consumed once a day before or after meals as advised by the doctor
Note: Grapefruit and grapefruit juice may interact with this medication; it may lead to potentially dangerous effects.