Active Ingredient: Ketorolac Tromethamine is the active component of this medication. It is a carboxylic acid derivative that has anti-inflammatory, analgesic, and antipyretic activities. This active ingredient inhibits the enzymes cyclooxygenase 1 and COX-2. As a consequence, COX-2, up-regulated at sites of inflammation and prevents the conversion of arachidonic acid to pro-inflammatory prostaglandins. This enzyme COX-1 helps prevents the normal prostaglandins that play a housekeeping role in the protection of the gastrointestinal tract, the regulation of renal blood flow, and platelet aggregation. It leads to the inhibition of COX-1 may be related to gastrointestinal toxicity, nephrotoxicity, and the inhibition of platelet aggregation.
Indications: This medicine is composed of Ketorolac, which is indicated for the short-term treatment of moderate to severe pain in adults. This medicine can be used before or after medical procedures or after surgery. Decreasing pain helps to recover more comfortably so as to get a return to the normal daily functions. Toradol is a nonsteroidal anti-inflammatory drug that blocks the production of certain natural substances in the body that induces inflammation. It also decreases swelling, pain, or fever. This medication shall not be used for mild or long-term painful conditions like arthritis.
Action Mechanism: This particular medication helps reduce the production of prostaglandins, which are chemicals that cells of the immune system produce. These chemicals cause the redness, fever, and pain of inflammation, and non-inflammatory pain. Toradol acts by blocking the enzymes that cells use to produce prostaglandins. This results in the reduction of pain as well as inflammation and symptoms like redness, swelling, fever, and pain.
Dosages: This effective medication is available for oral administration in a dosage as given below:
- 10 mg: This medication should be taken every 4 to 6 hours with a full glass of water, or as directed by the doctor
Do not lie down immediately after administrating this medicine.
What is Toradol?
Toradol is a nonsteroidal anti-inflammatory drug (NSAID). Toradol works by reducing hormones that cause inflammation and pain in the body.
How should Toradol be taken?
Toradol is usually given first as an injection, and then as an oral medicine. The injection is given into a muscle, or into a vein through an IV.
What should be avoided while taking Toradol?
Avoid drinking alcohol. It may increase the risk of stomach bleeding.
What other drugs will affect Toradol?
Advisable not to use Toradol if taking pentoxifylline, probenecid, aspirin, or other NSAID drugs which may include ibuprofen, acetaminophen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam, and others and others.
What precautions should be taken while taking Toradol?
Before using Toradol, tell the doctor or pharmacist if have allergies to it, or to aspirin or other nonsteroidal anti-inflammatory drugs-NSAIDs (such as ibuprofen, naproxen, celecoxib), or if have any other allergies.