AstraZeneca Toprol XL (extended release)


Toprol XL (extended release) is a popular brand medicine offered by a leading pharmaceutical company, AstraZeneca Pharmaceuticals. It is composed as an extended release tablet available in dosages 25 mg and 50 mg. It is administered orally with or without food as advised by the doctor. It has an active component Metoprolol Succinate, which is a beta-blocker medicine. This medicine is indicated for the treatment of high blood pressure, chest pain, heart attacks, and heart failure.

Manufacturer: AstraZeneca Pharmaceuticals

SKU: AstraZeneca Toprol XL (extended release) Categories: ,

Available Options

AstraZeneca Toprol XL (extended release) - 25mg

Pack SizePrice/unitPriceQtyAdd to cart
90 pills$0.25$22.50
120 pills$0.24$29.10
180 pills$0.23$41.85
240 pills$0.22$53.40
300 pills$0.21$63.00

AstraZeneca Toprol XL (extended release) - 50mg

Pack SizePrice/unitPriceQtyAdd to cart
90 pills$0.30$27.00
120 pills$0.29$34.92
180 pills$0.28$50.22
240 pills$0.27$64.08
300 pills$0.25$75.60


Active Ingredient: This medicine has active component beta-blocker, Metoprolol Succinate. This medication is a cardioselective competitive beta-1 adrenergic receptor antagonist that has antihypertensive properties. It shows devoid of intrinsic sympathomimetic activity. It reduces the rate and force of myocardial contraction and a diminished cardiac output. This is an active component that may also reduce the secretion of renin decrease in levels of angiotensin II. This decreases sympathetic activation, like vasoconstriction, aldosterone secretion.

Indications: This particular medication belongs to a class of drugs known as a beta-blocker. This medicine is indicated to treat chest pain, heart failure, and high blood pressure. Decreasing high blood pressure helps to prevent strokes, heart attacks, and kidney problems. Toprol XL blocks the action of certain natural chemicals in the body like epinephrine that affects the heart and blood vessels. It decreases the heart rate, blood pressure, and strain on the heart.

Action Mechanism: Blood pressure usually elevates due to blood vessels get tightened. This leads to a strain on the heart and maximizes the oxygen demand of the body. Toprol XL works by preventing norepinephrine or adrenalin from acting on beta receptors in blood vessels and in the heart. It results in the blood vessels to relax. So, this drug lowers the heart rate and decreases the heart’s demand for oxygen. As a consequence, it lowers blood pressure and reduces chest pain.

Dosages: This medicine is made available as an extended-release tablet in dosages as given below:

  • 25 mg:  This extended-release tablet must be taken as advised by the doctor, usually once a day
  • 50 mg:  It is advisable to take this medicine once a day as prescribed by the doctor

Note: This drug is not recommended in people with a serious heart problem, severe circulation problems, severe heart failure, or a history of slow heartbeats that lead to fainting.

What is Toprol?

Toprol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).

What is Toprol used for?

Toprol is used to treat angina (chest pain) and hypertension (high blood pressure). Toprol-XL is also used to lower the risk of death or needing to be hospitalized for heart failure.

What if missed a dose of Toprol?

Take a missed dose of Toprol as soon as remembered.

Is Toprol safe for nursing mother?

Toprol is not safe for nursing mother, it may inhibit lactation.

What other drugs will affect Toprol?

Many drugs can interact with Toprol, especially any other heart or blood pressure medications, especially digitalis, clonidine, diltiazem, verapamil, quinidine, propafenone.

Additional information


25mg, 50mg


90 pills, 120 pills, 180 pills, 240 pills, 300 pills


$0.25, $0.24, $0.23, $0.22, $0.21


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